Organic Synthesis

  • Custom Synthesis (> 95% purity, milligrams to kilograms scale)
  • Building blocks for Click chemistry
  • Linkers of antibodies: dry conjugate and other proteins
  • Key and advanced intermediates
  • Stable isotope labeled compounds

Process Research and Development

  • Scale up
  • kg scale synthesis of unnatural amino acids
  • Linkers and building blocks of click chemistry for proteins
  • Modification

Medicinal Chemistry

  • Hit to lead
  • Lead optimization and SAR development
  • Analog synthesis
  • Focus library via parallel synthesis

Chemistry, Manufacturing and Control (CMC)

  • cGMP manufacturing of GMP grade intermediates
  • Reference standard certification
  • Impurity and metabolite identification and characterization
  • Stability study
  • Regulatory document preparation and submission